Scientific Program
Final
scientific program

The Scientific Program will be presented as
Sections

|
Drug Substances
Polymorphs, hydrates, solvates, salts, enantiomers, molecular
compounds, complexes;
Screening methods for the selection of the most favorable drug
substances;
Physico- chemical characterization;
Chemical stabilities and kinetics in respect to temperature, oxygen,
water, solvents and chemical reactants;
Physical stabilities, transformation scheme and kinetics in respect to
temperature, pressure, mechanical forces, light;
Solubility and the dissolution rate in respect to pH;
Chemical and enantiomeric impurities,
Physical impurities in respect to the solid state impurities and to the
degree of amorphicity
|

|
Excipients and Polymers
Characterization and compatibility
|

|
Drug Products
Manufacturing, aging, and release;
Solid dosage forms, solid dispersions, semi-solid forms, liquid forms,
microemulsions, encapsulations, controlled release systems, freeze
dried forms
|

|
Site-specific Drug Delivery
Interactions drug-receptor, transport and diffusion mechanisms
|

|
Methods of Physical Chemistry and
Instrumentation
Thermodynamics, thermal analysis classical and modulated versions,
calorimetry, spectroscopical methods such as IR and Raman spectroscopy,
X-ray diffraction methods (temperature and humidity resolved), NMR methods
specially solid-state NMR, microscopy,
moisture sorption analysis, rheology, new techniques;
Instrumental procedures and properties such as calibration and
calibration standards, sensitivity, thermal resolution; validation
procedures.
|
Timetable
Sunday, September 10, 2006
|
14:00 – 16:00
|
Registration for the Conference
|
|
14:00
|
Meeting of theBoard Members
|
|
16:00
|
Opening of the PhandTA 9
|
|
16:10
– 19:00
|
Main
Lectures
|
|
19:30
|
Aperitif
|
|
Monday, September 11, 2006
|
08:30
– 18:00
|
Award and Plenary Lectures,
Key and Short Communications,
Poster Sessions,
Exhibition
of Instruments
|
Tuesday,
September 12, 2006
|
08:30
– 18:00
|
Wednesday,
September 13, 2006
|
08:30
– 12:00
|
|
Wednesday, September 13, 2006
|
13:00
– 18:00
|
Workshops on selected topics
|
|
Tuesday, September 12, 2006
|
20:00
|
Conference
Dinner
|
|
Current list of
Plenary lectures in alphabetic order)

|
Thiomers: A potent tool for the
non-invasive administration of efflux pump substrates?
Andreas Bernkop Schnürch
Institute for Pharmacy, University of Innsbruck, Austria
|

|
Kinetic Aspects of Polymorphism in
Respect to Drug Substances
Elena V. Boldyreva
Novosibirsk State University, Russian Academy of Sciences, Novosibirsk,
RUS
|

|
Investigation of Carbamazepine/Acetone
Solvate Formation over a Range of Temperatures using Vapor Sorption
Techniques
Daniel Burnetta, Frank Thielmannb
a Surface Measurement Systems NA, Allentown PA, USA
b Surface Measurement Systems Ltd., London, UK
|

|
High resolution powder diffraction
studies of polymorphism in pharmaceutical compounds
W.I.F David
ISIS Facility, Rutherford Appleton Laboratory, Chilton, Oxfordshire, UK
|

|
Comparison of quantitative methods for
analysis of polyphasic pharmaceutical systems
D. Giron, S. Monnier, F. Stowasser, M. Mutz, P. Piechon, M. Bellus, K. Schülze
Novartis Pharma AG, Basel, CH
|

|
Crystal Polymorphism in Pharmaceuticals:
A Statistical Approach
Ulrich J. Griesser, Doris E. Braun
Institute for Pharmacy,
University of Innsbruck, A
|

|
Screening Procedures and Selection of the best
Solid-State Form of a Drug Substance
Fritz Blatter,
Rolf Hilfiker, Markus von Raumer
Solvias AG, Basel, CH |
|
Investigation of pharmaceuticals by
Infrared and Raman micro spectroscopy
Gernot Hoehne, Albrecht Rager, Matthias Boese
Bruker Optik GmbH, Ettlingen, D
|
|
Characterization and stability of lipid
extrudates
P. Kleinebudde, C. Reitz
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University Duesseldorf, D
|
|
Patents and Polymorphs
Paul Georg Maué
Solvias AG, Basel, CH
|
|
A new approach for compressibility and
compactibility characterization of materials pure and in mixture
Katharina M. Picker-Freyer, Karsten Hauschild
Institute of Pharmaceutics and Biopharmaceutics
Martin-Luther-University Halle-Wittenberg, D
|
|
The influence of surfactants on passive
diffusion and active efflux of drugs
Anna Seelig
Biocenter, University of Basel, CH
|
|
When peptide meets lipid: Greasy
folding. Thermodynamics of lipid-protein interaction
Joachim Seelig
Biocenter, University of Basel, CH |
<
|
Pharmacy and Thermal Analysis at the
Institute of Pharmacy in Düsseldorf
Nora Anne Urbanetz
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University Duesseldorf, D
|
Current list of
further contributions (in alphabetic order)

|
Crystal Polymorphism of
(S)-1,1,2-Triphenyl-1,2-ethanediol
Rafael Barbas, Rafel Prohens, Cristina Puigjaner
University of Barcelona, E
|
 |
A Compatible System for Microscale HTS Raman and
X-ray diffraction
M. Bellus, G. Morani, S. Monnier, F. Stowasser, D.Giron,
Novartis Pharma AG, Basel, CH |
|
Conformational color polymorphism and
solvates of Picryltoluidine
D.E. Brauna, R.K.R. Jettia, V. Kahlenbergb,
U.J. Griessera
a Institute of Pharmacy, University of Innsbruck, A
b Institute of Mineralogy and Petrography, University of
Innsbruck, A |
 |
Thermodynamic Characteristics of
Collagen in Composition of Pathologic Tissues
N. Esipovaa, J., V. Tumanyana, E. Katovskaiab,
M. Gorgoshidzec, I. Mesropyanc, Monaselidzec
a Enhelgardt Institute of Molecular Biology, Moscow, RUS
b State Establishment Medical Social Committee of Experts,
Moscow, RUS
c E. Andronikashvili Institute of Physics, Tbilisi, Georgia |
 |
Solid State Properties
and Stability of Crystal Forms of Pentamidine Isethionate
Katharina Fucke, Ulrich J. Griesser
Institute of Pharmacy, University of Innsbruck, A |
|
Studies of interaction between heavy
metal ions and C-phycocyanin from S.platensis
E. Gelagutashvili, A. Khizanishvili
E.L. Andronikashvili Institute of Physics,
Academy of Sciences, Tbilisi, Georgia
|
|
Monitoring Galenical Process Development
by Chemical Imaging
C. Gendrina,b, Y. Roggoa, C. Spiegela,
C. Colletb
a F. Hoffmann-La Roche Ltd., Basel, Switzerland
b LSIIT, Louis Pasteur University, Strasbourg, France
|
 |
Membrane Proteins in Thin
Films: A DSC Study
A. Geoffroya,
M Stolzb,
E. Lewitzkib,
M. von Raumera,
E. Grellb
a Solvias AG, Basel, CH
b Max-Planck-Institute of Biophysics, Frankfurt, D |
 |
Oscillating temperature reaction calorimetry and modulated DSC for
polymer synthesis and characterization Florin Dana, Jean-Pierre Grolierb
a "Gh. Asachi" Technical University Iasi, Romania
b Blaise Pascal University, 63177 Aubière, France |

|
Pursuing Leuprolide release from poly
lactide-co-glycolide polymer by means of different spectroscopic
methods
Kamahldin Haghbeena, Nargess Bahmanyarb, Mina
Evinic, Hamid Mobedid
a National Institute for Genetic Engineering and
Biotechnology
b Science and research branch, Islamic azad university
c Institute of Biochemistry and Biophysics of Tehran
University
d Iran Polymer Institute
|
|
Surface structure analysis of monolayer
and its application for nano-structure control
S. Y. Junga, H. Yoshidab,c
a Graduate School of Engineering, Tokyo Metropolitan
University, J
b Faculty of Urban Enviromental Sciences, Tokyo Metropolitan
University, J
c CREST-JST, J |

|
TMA - elucidating the film formation of
the dry coating process
C.D. Kablitz, N.A. Urbanetz
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University Duesseldorf, D
|

|
Residual Solvents beyond the ICHQ3C
guideline
Kyriakos Kachrimanisa, Katharina Fuckeb, Michael
Noisternigb, Ulrich J. Griesserb
a Department of Pharmaceutical Technology, Aristotle
University of Thessaloniki, GR
b Institute of Pharmacy, University of Innsbruck, A
|

|
Influence of DSC and TG Test Conditions
on the Thermal Behavior of Diclofenac Sodium
Gabriele Kaiser, Ekkehard Füglein, Elena Moukhina
NETZSCH-Gerätebau GmbH, Selb, D
|

|
Thermodynamics and Kinetics applied to the Stability of Polymorphs
E. Marti
APCh Marti
Consulting, Basel, CH
|
 |
Automated Multi-sample Moisture
Sorption Analysis Erwin Martia, Ulrich J.
Griesserb
a APCh Marti
Consulting, Basel, CH
>b Institute for Pharmacy,
University of Innsbruck, A |

|
Characterization of drug substances by
Thermal Analysis
Christine Mayoux
Setaram, Caluire, F
|
 |
Microcalorimetry and routine control of amorphous
content, examples
S. Monnier, T. Buser, D. Giron, M. Mutz
Novartis Pharma AG, Basel, CH |
 |
Use of highthroughput microcalorimeter for faster
determination of amorphous content
M. Mutz, A. Motreff, S. Monnier, T. Buser, P. Schwab, D. Giron
Novartis Pharma AG, Basel, CH |

|
The use of moisture sorption technique
in quantification of the degree of disorder in micronized salbutamol
sulphate
V.
Mykhaylova, M. Gorny, M. Jakobs, N.A. Urbanetz
Heinrich-Heine-University Duesseldorf, D
|

|
Reactivity of Piroxicam in Reaction of
Mechanochemical Acylation
S.A. Myza,b, N.A. Pankrushina,b,c, T.P.
Shakhtshneidera,b, A.S. Medvedevad,
L.P. Safronovad, V.V. Boldyreva,b
a Institute of Solid State Chemistry and Mechanochemistry
,Novosibirsk, RUS
b Novosibirsk State University, RUS
c Novosibirsk Institute of Organic Chemistry and
Mechanochemistry, RUS
d A. E. Favorsky Irkutsk Institute of Chemistry, RUS
|

|
Kinetic studies guide to effective
administration of Tyrosinase Inhibitor
Fatemeh Saied Nematpoura,c, Kamahldin Haghbeenb,
Ramazanali Khavarinejada, Akbar Safipour Afsharc
a Islamic Azad University (Science and Research Branch),
Tehran, Iran
b The National Institute for Genetic Engineering and
Biotechnology, Tehran, Iran
c Biology Department of Islamic Azad University (Neyshabour
Branch), Tehran, Iran
|

|
Characterization of solvates and crystal
polymorphs of (R/S)- Bupivacaine hydrochloride
V. Niederwangera, R.K.R. Jettia, V. Kahlenbergb,
U. J. Griessera
a Institute of Pharmacy, University of Innsbruck, A
b Institute of Mineralogy and Petrography, University of
Innsbruck, A
|

|
Thermogravimetric Analysis in Combination with FTIR
Monika Schennen, Wolfgang Kunze
Waters GmbH UB TA Instruments, Eschborn, D
|

|
Obtaining of amorphous drug –
polyvinylpyrrolidone mixtures by cryogenic grinding
T.P. Shakhtshneidera,b, F. Danèdec, F. Capetc,
J.F. Willartc, M. Descampsc, L. Paccouc,
E.V. Boldyrevaa,b, V.V. Boldyreva,b
a Institute of Solid State Chemistry and Mechanochemistry,
Novosibirsk, RUS
b Novosibirsk State University, RUS
c Universitè de Lille, Villeneuve d’Ascq, F
|

|
Differences in the amorphous state in
differently processed pharmaceutical powders
Frank Thielmanna, Daniel Burnettb
a Surface Measurement Systems Ltd., London, UK
b Surface Measurement Systems NA, Allentown PA, USA
|

|
Determination of freezing and
nonfreezing bound water to k-carrageenan and microcrystalline cellulose using differential
scanning calorimetry
M. Thommes, P. Kleinebudde
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University Duesseldorf, D
|
 |
Characterisation of New Solvates
of Amiloride-HCl
M.C. Tischler, B. Binna, U.J. Griesser
Institute of Pharmacy, University of Innsbruck, A |

|
Raman Spectroscopy: An emerging analyzer
tool for the pharmaceutical industry
Carsten Uerpmann
Kaiser Optical Systems, Ecully, F
|

|
Aqueous Solutions of Nonelectrolytes:
Thermodynamic Investigations.
E.
Wilhelm
Institut für Physikalische Chemie, Universität Wien, A
|

|
Effect of CO2 and N2
Pressures on Isotropic transition of Amphiphilic Liquid Crystal
Di-block Copolymer
T. Yamadaa,b, S.A.E. Boyera,b,e, T. Iyodac,e,
H. Yoshidad,e, J-P. E. Grolierb
a Graduate School of Engineering, Tokyo Metropolitan
University, J
b Blaise Pascal University, Aubière, France
c Tokyo Institute of Technology, Yokohama, Kanagawa, J
d Faculty of Urban Environmental Science, Tokyo Metropolitan
University, J
e CREST-JST, Japan
|

|
Evaluation of Compatibility in Polymer
Blend Systems By Simultaneous DSC-FTIR Measurement
Hirohisa Yoshida
Tokyo Metropolitan University, Urban Environmental Science, Applied
Chemistry, J
|

|