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Conferences - PhandTA 9

Scientific Program

   Final scientific program  

 

The Scientific Program will be presented as

 

Award Lectures (AL, 60 min)

    Current list of contributions

 

Plenary Lectures (PL, 50 min)

 

 

Key Communications (KC, 30 min)

 

 

Short Communications (SC, 20 min)

 

 

Posters (PO)

 

Workshops on Wednesday

 

Sections

Drug Substances
Polymorphs, hydrates, solvates, salts, enantiomers, molecular compounds, complexes;
Screening methods for the selection of the most favorable drug substances;
Physico- chemical characterization;
Chemical stabilities and kinetics in respect to temperature, oxygen, water, solvents and chemical reactants;
Physical stabilities, transformation scheme and kinetics in respect to temperature, pressure, mechanical forces, light;
Solubility and the dissolution rate in respect to pH;
Chemical and enantiomeric impurities,
Physical impurities in respect to the solid state impurities and to the degree of amorphicity
 

Excipients and Polymers
Characterization and compatibility

Drug Products
Manufacturing, aging, and release;
Solid dosage forms, solid dispersions, semi-solid forms, liquid forms, microemulsions, encapsulations, controlled release systems, freeze dried forms

Site-specific Drug Delivery
Interactions drug-receptor, transport and diffusion mechanisms

Methods of Physical Chemistry and Instrumentation
Thermodynamics, thermal analysis classical and modulated versions, calorimetry, spectroscopical methods such as IR and Raman spectroscopy, X-ray diffraction methods (temperature and humidity resolved), NMR methods specially solid-state NMR, microscopy,
moisture sorption analysis, rheology, new techniques;
Instrumental procedures and properties such as calibration and calibration standards, sensitivity, thermal resolution; validation procedures.

Timetable

Sunday, September 10, 2006

14:00 – 16:00

Registration for the Conference

 

14:00

Meeting of theBoard Members

 

16:00

Opening of the PhandTA 9

 

16:10 – 19:00

Main Lectures

 

19:30

Aperitif


Monday, September 11, 2006

08:30 – 18:00

Award and Plenary Lectures,
Key and Short Communications,
Poster Sessions,
Exhibition of Instruments

Tuesday, September 12, 2006

08:30 – 18:00

Wednesday, September 13, 2006

08:30 – 12:00


Wednesday, September 13, 2006

13:00 – 18:00

Workshops on selected topics


Tuesday, September 12, 2006

20:00

Conference Dinner


Current list of Plenary lectures in alphabetic order)

 

Thiomers: A potent tool for the non-invasive administration of efflux pump substrates?
Andreas Bernkop Schnürch
Institute for Pharmacy, University of Innsbruck, Austria

 

Kinetic Aspects of Polymorphism in Respect to Drug Substances
Elena V. Boldyreva
Novosibirsk State University, Russian Academy of Sciences, Novosibirsk, RUS

 

Investigation of Carbamazepine/Acetone Solvate Formation over a Range of Temperatures using Vapor Sorption Techniques
Daniel Burnetta, Frank Thielmannb
a Surface Measurement Systems NA, Allentown PA, USA
b Surface Measurement Systems Ltd., London, UK

High resolution powder diffraction studies of polymorphism in pharmaceutical compounds
W.I.F David
ISIS Facility, Rutherford Appleton Laboratory, Chilton, Oxfordshire, UK

 

Comparison of quantitative methods for analysis of polyphasic pharmaceutical systems
D. Giron, S. Monnier, F. Stowasser, M. Mutz,
P. Piechon, M. Bellus, K. Schülze
Novartis Pharma AG, Basel, CH

 

Crystal Polymorphism in Pharmaceuticals: A Statistical Approach
Ulrich J. Griesser, Doris E. Braun
Institute for Pharmacy, University of Innsbruck, A

Screening Procedures and Selection of the best Solid-State Form of a Drug Substance
Fritz Blatter, Rolf Hilfiker, Markus von Raumer
Solvias AG, Basel, CH
Investigation of pharmaceuticals by Infrared and Raman micro spectroscopy
Gernot Hoehne, Albrecht Rager, Matthias Boese
Bruker Optik GmbH, Ettlingen, D
Characterization and stability of lipid extrudates
P. Kleinebudde, C. Reitz
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University Duesseldorf, D
Patents and Polymorphs
Paul Georg Maué
Solvias AG, Basel, CH

A new approach for compressibility and compactibility characterization of materials pure and in mixture
Katharina M. Picker-Freyer, Karsten Hauschild
Institute of Pharmaceutics and Biopharmaceutics
Martin-Luther-University Halle-Wittenberg, D
The influence of surfactants on passive diffusion and active efflux of drugs
Anna Seelig
Biocenter, University of Basel, CH

When peptide meets lipid: Greasy folding. Thermodynamics of lipid-protein interaction
Joachim Seelig
Biocenter, University of Basel, CH
< Pharmacy and Thermal Analysis at the Institute of Pharmacy in Düsseldorf
Nora Anne Urbanetz
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University Duesseldorf, D

Current list of further contributions (in alphabetic order)

Crystal Polymorphism of (S)-1,1,2-Triphenyl-1,2-ethanediol
Rafael Barbas, Rafel Prohens, Cristina Puigjaner
University of Barcelona, E
A Compatible System for Microscale HTS Raman and X-ray diffraction
M. Bellus, G. Morani, S. Monnier, F. Stowasser, D.Giron,
Novartis Pharma AG, Basel, CH
Conformational color polymorphism and solvates of Picryltoluidine
D.E. Brauna, R.K.R. Jettia, V. Kahlenbergb, U.J. Griessera
a Institute of Pharmacy, University of Innsbruck, A
b Institute of Mineralogy and Petrography, University of Innsbruck, A
Thermodynamic Characteristics of Collagen in Composition of Pathologic Tissues
N. Esipovaa, J., V. Tumanyana, E. Katovskaiab, M. Gorgoshidzec, I. Mesropyanc, Monaselidzec
a Enhelgardt Institute of Molecular Biology, Moscow, RUS
b State Establishment Medical Social Committee of Experts, Moscow, RUS
c E. Andronikashvili Institute of Physics, Tbilisi, Georgia
Solid State Properties and Stability of Crystal Forms of Pentamidine Isethionate
Katharina Fucke, Ulrich J. Griesser
Institute of Pharmacy, University of Innsbruck, A
Studies of interaction between heavy metal ions and C-phycocyanin from S.platensis
E. Gelagutashvili, A. Khizanishvili
E.L. Andronikashvili Institute of Physics, Academy of Sciences, Tbilisi, Georgia

Monitoring Galenical Process Development by Chemical Imaging
C. Gendrina,b, Y. Roggoa, C. Spiegela, C. Colletb
a F. Hoffmann-La Roche Ltd., Basel, Switzerland
b LSIIT, Louis Pasteur University, Strasbourg, France

Membrane Proteins in Thin Films: A DSC Study
A. Geoffroya, M Stolzb, E. Lewitzkib, M. von Raumera, E. Grellb
a Solvias AG, Basel, CH
b
Max-Planck-Institute of Biophysics, Frankfurt, D

Oscillating temperature reaction calorimetry and modulated DSC for polymer synthesis and characterization
Florin Dana, Jean-Pierre Grolierb
a "Gh. Asachi" Technical University Iasi, Romania
b Blaise Pascal University, 63177 Aubière, France

 

Pursuing Leuprolide release from poly lactide-co-glycolide polymer by means of different spectroscopic methods
Kamahldin Haghbeena, Nargess Bahmanyarb, Mina Evinic, Hamid Mobedid
a National Institute for Genetic Engineering and Biotechnology
b Science and research branch, Islamic azad university
c Institute of Biochemistry and Biophysics of Tehran University
d Iran Polymer Institute
Surface structure analysis of monolayer and its application for nano-structure control
S. Y. Junga, H. Yoshidab,c
a Graduate School of Engineering, Tokyo Metropolitan University, J
b Faculty of Urban Enviromental Sciences, Tokyo Metropolitan University, J
c CREST-JST, J

 

TMA - elucidating the film formation of the dry coating process
C.D. Kablitz, N.A. Urbanetz
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University Duesseldorf, D

Residual Solvents beyond the ICHQ3C guideline
Kyriakos Kachrimanisa, Katharina Fuckeb, Michael Noisternigb, Ulrich J. Griesserb
a Department of Pharmaceutical Technology,  Aristotle University of Thessaloniki, GR
b Institute of Pharmacy, University of Innsbruck, A

Influence of DSC and TG Test Conditions on the Thermal Behavior of Diclofenac Sodium
Gabriele Kaiser, Ekkehard Füglein, Elena Moukhina
NETZSCH-Gerätebau GmbH, Selb, D

Thermodynamics and Kinetics applied to the Stability of Polymorphs
E. Marti
APCh Marti Consulting, Basel, CH

Automated Multi-sample Moisture Sorption Analysis
Erwin Martia, Ulrich J. Griesserb
a APCh Marti Consulting, Basel, CH
>b Institute for Pharmacy, University of Innsbruck, A

 

Characterization of drug substances by Thermal Analysis
Christine Mayoux
Setaram, Caluire, F

Microcalorimetry and routine control of amorphous content, examples
S. Monnier, T. Buser, D. Giron, M. Mutz
Novartis Pharma AG, Basel, CH
Use of highthroughput microcalorimeter for faster determination of amorphous content
M. Mutz, A. Motreff, S. Monnier, T. Buser, P. Schwab, D. Giron
Novartis Pharma AG, Basel, CH

 

The use of moisture sorption technique in quantification of the degree of disorder in micronized salbutamol sulphate
V. Mykhaylova, M. Gorny, M. Jakobs, N.A. Urbanetz
Heinrich-Heine-University Duesseldorf, D

Reactivity of Piroxicam in Reaction of Mechanochemical Acylation
S.A. Myza,b, N.A. Pankrushina,b,c, T.P. Shakhtshneidera,b, A.S. Medvedevad,
L.P. Safronovad, V.V. Boldyreva,b
a Institute of Solid State Chemistry and Mechanochemistry ,Novosibirsk, RUS
b Novosibirsk State University, RUS
c Novosibirsk Institute of Organic Chemistry and Mechanochemistry, RUS
d A. E. Favorsky Irkutsk Institute of Chemistry, RUS

 

Kinetic studies guide to effective administration of Tyrosinase Inhibitor
Fatemeh Saied Nematpoura,c, Kamahldin Haghbeenb, Ramazanali Khavarinejada, Akbar Safipour Afsharc
a Islamic Azad University (Science and Research Branch), Tehran, Iran
b The National Institute for Genetic Engineering and Biotechnology, Tehran, Iran
c Biology Department of Islamic Azad University (Neyshabour Branch), Tehran, Iran

Characterization of solvates and crystal polymorphs of (R/S)- Bupivacaine hydrochloride
V. Niederwangera, R.K.R. Jettia, V. Kahlenbergb, U. J. Griessera
a Institute of Pharmacy, University of Innsbruck, A
b Institute of Mineralogy and Petrography, University of Innsbruck, A

Thermogravimetric Analysis in Combination with FTIR
Monika Schennen,  Wolfgang Kunze
Waters GmbH UB TA Instruments, Eschborn, D

Obtaining of amorphous drug – polyvinylpyrrolidone mixtures by cryogenic grinding
T.P. Shakhtshneidera,b, F. Danèdec, F. Capetc, J.F. Willartc, M. Descampsc, L. Paccouc, E.V. Boldyrevaa,b, V.V. Boldyreva,b
a Institute of Solid State Chemistry and Mechanochemistry, Novosibirsk, RUS
b Novosibirsk State University, RUS
c Universitè de Lille, Villeneuve d’Ascq, F

 

Differences in the amorphous state in differently processed pharmaceutical powders
Frank Thielmanna, Daniel Burnettb
a Surface Measurement Systems Ltd., London, UK
b Surface Measurement Systems NA, Allentown PA, USA

 

Determination of freezing and nonfreezing bound water to k-carrageenan and microcrystalline cellulose using differential scanning calorimetry
M. Thommes, P. Kleinebudde
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University Duesseldorf, D

Characterisation of New Solvates of Amiloride-HCl
M.C. Tischler, B. Binna, U.J. Griesser
Institute of Pharmacy, University of Innsbruck,  A

Raman Spectroscopy: An emerging analyzer tool for the pharmaceutical industry
Carsten Uerpmann
Kaiser Optical Systems, Ecully, F

Aqueous Solutions of Nonelectrolytes: Thermodynamic Investigations.
E. Wilhelm
Institut für Physikalische Chemie, Universität Wien, A

Effect of CO2 and N2 Pressures on Isotropic transition of Amphiphilic Liquid Crystal Di-block Copolymer
T. Yamadaa,b, S.A.E. Boyera,b,e, T. Iyodac,e, H. Yoshidad,e, J-P. E. Grolierb
a Graduate School of Engineering, Tokyo Metropolitan University, J
b Blaise Pascal University, Aubière, France
c Tokyo Institute of Technology, Yokohama, Kanagawa, J
d Faculty of Urban Environmental Science, Tokyo Metropolitan University, J
e CREST-JST, Japan

 

Evaluation of Compatibility in Polymer Blend Systems By Simultaneous DSC-FTIR Measurement
Hirohisa  Yoshida
Tokyo Metropolitan University, Urban Environmental Science, Applied Chemistry, J

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