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Conferences - PhandTA 8
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Scientific Program
ORAL CONTRIBUTIONS
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IGC determinations of solubility parameter for characterization
of pharmaceutical excipients Katarzyna Adamska, Adam Voelkel
Poznań University
of Technology, Institute of Chemical Technology and Engineering,
Poland
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Mercury Intrusion Porosimetry: Determination of Pore Size,
Particle Size and Density of Dry and Wet Materials
J. Adolphs
Porotec GmbH, Hofheim, Germany |
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Correlation between Molecular Mobility and Isothermal
Crystallization Kinetics for an Amorphous Pharmaceutical Drug
Substance Investigated by Dielectric Techniques
J. Aliéa, J. Menegottob, S. Byardb,
M. Bauerb, C. Lacabannea
a Polymer Physics Laboratory, Toulouse, France
b Sanofi-Synthelabo Research,
France and UK |
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Biomacromolecules at work: watching the details by solution NMR
methods
M. Allana, M. Barfieldb,
F. Cordiera, J. Engela,
D. Häussingera, P. Jensena,
J. Kahmanna, H.J. Sassa,
C. Thompsona, S. Grzesieka
a Biozentrum, University of Basel, CH 4056
Basel, Switzerland
b Department of Chemistry, University of
Arizona, Tucson, AZ 85721, USA |
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WETSYS: A New Tool to Explore the Effect of a
Humid Atmosphere on a Sample
R. Andre, R. Naumann
Setaram Instrumentation, Caluire, France |
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Measurement of Solvation Energies, the Key to
Understand Partitioning and Passive Transport of Drugs
A. Bauer-Brandla, G. Perlovicha,b
a
Institute of Pharmacy, University of Tromsoe,
Norway
b
Institute of Solution Chemistry, Russian Academy of
Sciences, Ivanovo, Russia |
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Chemometric analysis of calorimetric data - and the development
of a photocalorimeter for use in photostability studies of
pharmaceuticals
Anthony E. Beezer
School of Pharmacy, University of London, United Kingdom |
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Pharmaceutical evaluation of early development candidates:
Miniaturized and automated early Polymorphism investigations
Harald Berchtold, Martin Bröckelmann, Winfried Heyse, Norbert
Nagel, Laure Viola
Aventis, GPD Solid State Characterization, Frankfurt/Main, Germany |
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New Developments in Screening for Pharmaceutical Salts and
Polymorphs: High Throughput versus Conventional Laboratory Scale
Experimentation
Fritz Blatter, Rolf Hilfiker, Markus von Raumer
Solvias AG, Basel, Switzerland |
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Co-crystallization - The Supramolecular Synthesis
Roland Boesea, M. T. Kirchnera,
A. Gehrkea, T. Bendeleb, R. Sustmannb
a Institut für Anorganische Chemie, Univ. Duisburg-Essen,
Essen, Germany
b Institut für Organische Chemie, Univ. Duisburg-Essen,
Essen, Germany |
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A new polymorph of glycine formed at high
pressure
Elena V. Boldyrevaa,b,
S.N. Ivashevskaya
a,c,
H. Ahsbahsd, H. Sowad, H.-P. Webere
a
Novosibirsk State University, Russia
b the Russian Academy of Sciences, Novosibirsk, Russia
c Karelian Scientific Center Russian Academy of Sciences,
Petrozavodsk, Russia
d Institute of Mineralogy, Philipps-Universitaet
Marburg/Lahn, Germany
e Swiss-Norwegian Beamlines ESRF, Grenoble, France |
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Concentration of a supercritical gas absorbed in a polymer and
the concomitant change in volume of the polymer
Séverine A. E. Boyera,b,
Jean-Pierre E. Groliera
a Laboratory of Thermodyn.
of Solutions
+ Polymers, B.
Pascal Univ., Aubière, France
b Institut Francais du Pétrole,
Lyon-Vernaison, France |
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A Novel Fluorescence Assay for DNA Synapsis and Ligation
David T. Cramba, Dennis Merklea,b,
Susan P. Lees-Millerc
a Department of Chemistry,
University of Calgary, Canada
b Department of Biochemistry and
Molecular Biology, University of Calgary, Canada |
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Identification, Crystal Structure Solution and Refinement of
Stable and Metastable Pharmaceutical Compounds by Powder Diffraction
W. I. F. Davida,
K. Shanklanda,
R. M. Ibbersona,
C. R. Pulhamb
a ISIS Facility, Rutherford Appleton Laboratory, Chilton, United
Kingdom
b School of Chemistry, The University of Edinburgh,
United Kingdom |
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Mechanical Activation and Mechanical Alloying of
Pharmaceutical Compounds
M. Descamps, J.F. Willart, S. Desprez, A. De Gusseme, V. Caron
LDSMM, UMR CNRS 8024, University Lille, Villeneuve d'Ascq, France
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Crystal properties impacting on milling induced disorder
Robert T. Forbes
Drug Delivery Group, School of Pharmacy, University of Bradford,
United Kingdom |
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The Lattice Energy of Organic Compounds:
Thermodynamic Facts and Computer Simulation
Angelo Gavezzotti
Department of Structural Chemistry,
University of Milano, Italy |
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Binding of Cu(II) and Cd(II) ions with DNA from Spirulina
Platensis
Eteri Gelagutashvilia,
David Djoxadzeb, Liguri
Mosulishvilia
a E.L.Andronikashvili Institute of
Physics, Georgian Acad. Sci., Tbilisi,
Georgia
b Tbilisi State University,
Georgia |
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Challenging analytical development for polyphasic new entities,
case studies
D. Giron, S. Monnier, M. Mutz, F. Stowasser
Chemical and Analytical Development, Novartis Pharma AG, Basel,
Switzerland |
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Benefits and Limitations of Crystal Structure Determinations for
the Understanding of Host-Guest Supramolecular Complexation
A. Grandeurya, S. Petita,
G. Gouhierb, S. Costea,
G. Coquerela
a Sciences et Methodes Separatives,
University of Rouen, France
b IRCOF, University of Rouen,
France |
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Award for "Applied
Physical
Chemistry"
Influences of Mechanical Stresses on the Crystal and Molecular
Structure of Piroxicam
David J.W. Granta, Agam R.
Shetha, Francis X. Mullerb
a Department of Pharmaceutics,
University of Minnesota, Minneapolis, USA,
b GlaxoSmithKline, USA |
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Characterization, Stability and Structure of Pharmaceutical
Hydrates
David J.W. Grant
Department of Pharmaceutics, University of Minnesota, Minneapolis,
USA |
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Crystal Forms of Thiamine Hydrochloride (Vitamin B1): New
analytical Data of a compound with an intriguing solid state history
Ulrich Griesser
Department of Pharmaceutical Technology, University of Innsbruck,
Austria |
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Ternary Solid-Liquid Equilibria for Crystallization of
Pharmaceutical Components
Jean-Pierre E. Groliera,
Mohammad H. Hamedib
a Laboratory of Thermodyn. of
Solutions
+ Polymers, B.
Pascal Univ., Aubière, France
b Mechanical Engineering
Department, K.N. Toosi University, Tehran, Iran |
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Phase transition of hydrogen-bonded supramolecular assembly
consisting of amphoteric molecules studied by DSC-XRD and DSC-FTIR
Daisuke Ishiib, Takeshi Yamadaa,
Hirohisa Yoshidaa,c, Masaru
Nakagawab,
Tomokazu Iyodab,c
a Dep. of
Applied Chemistry, Graduate School of Engineer.,
Tokyo Metropolitan Univ., Japan
b Chemical Research Laboratory,
Tokyo Inst. of Technol.,
Nagatsuda, Yokohama, Japan
c CREST, Japan
Science and Technology Corporation, Japan |
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On-line monitoring of Solvent Mediated Polymorphic Conversion by
Isothermal Microcalorimetry
Peter Johansson
Thermometric AB, Järfälla, Sweden |
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Thermal Safety Calorimetry - Comparison of
Measurements
J. Hakla,
Ralf Meierb
a CALS AG, CH-4123 Allschwil, Switzerland
b
Systag
Systemtechnik Deutschland GmbH, Rosbach, Germany |
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Polymorphism and structural phase transitions in sodium
disilicate (Na2Si2O5)
Volker Kahlenberg
Inst. of Mineralogy and Petrography, University of Innsbruck,
Austria |
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DSC Signal Optimization with BeFLAT® and ISSP®
in Pharmaceutical Applications
Erwin Kaisersberger, Markus Hollering, Elena Moukhina
Netzsch Gerätebau GmbH, Selb, Germany |
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Thermodynamic and kinetic studies on R(+) and
S(-)-2,2'-dihydroxy-1-,1'-binaphthyls in solid state
Takayoshi Kimura, Yumi Toshima, Kousuke Morishima, Masashi Matsumato,
Manami Miyamoto, Tadashi Kamiyama
Dep. of Chemistry, Faculty of Sci.
+ Technol., Kinki
University, Higashi-osaka Japan |
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Electron Crystallography – a tool to solve polymorphic structures
?
Ute Kolb
Institute of Physical Chemistry, Johannes Gutenberg University,
Mainz, Germany |
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Review, New Insights and Selected Examples of Desolvation
Investigations
Franck Mallet, Samuel Petit, Gérard Coquerel
Sciences et Methodes Separatives, University of Rouen, France |
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Resolution of Differential Scanning Calorimeters
Erwin Martia, Erwin Kaisersbergerb,
Wolf-Dieter Emmerichb
a APCh Marti Consulting, Basel,
Switzerland
b Netzsch Gerätebau GmbH, Selb,
Germany |
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Interactions of detergents with lipid bilayers and monolayers
studied by Isothermal Titration Calorimetry and Infrared Reflection
Absorption Spectroscopy
Annette Meister, Andreas Kerth, Katja Beyer, Alfred Blume
Martin Luther University Halle-Wittenberg, Institute of Physical
Chemistry, Germany |
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Did you got all Information from your Sample
?
Gisbert Naundorfa, Tim Mannb,
Paul Gabbottb
a PerkinElmer (Schweiz) AG,
Schwerzenbach, Switzerland
b PETA Solutions, Beaconsfield, United
Kingdom |
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Solid State Pharmaceuticals: Thermal and Photo- Stability
Csaba Novaka, Michael E. Brownb,
Beverley D. Glassc
a Budapest Univ.
of Technol. +Econ.,
Research Group of Techn.
Analyt. Chem.
,Hungary
b Chemistry Department, Rhodes
University, Grahamstown, South Africa
c School of Pharmacy and Molecular
Sciences, James Cook University, Townsville, Australia |
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Application of Raman and IR Spectroscopy in Pharmaceutical
Development
Sabine Pfeffer-Hennig, Miriam Bellus
Chemical and Analytical Development, Novartis Pharma AG, Basel,
Switzerland |
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Chiral selectivity of the crystal packing in binary systems
of enantiomers. A new way to quantify chirality
Ludovic Renou, Servane Coste, Gérard Coquerel
UC2M2, University of Rouen, France |
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Investigation of weak transitions in pharmaceutically relevant
compounds
Rudolf Riesen, Matthias Wagner
Mettler-Toledo GmbH, Schwerzenbach, Switzerland |
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Non-destructive Analysis by Raman Spectroscopy
Bernhard Schrader
Physical and Theoretical Chemistry, University of Essen, Germany |
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The effect of halogenation on membrane binding and permeation
Anna Seelig
Department of Biophysical Chemitsry, Biocenter, University of Basel,
Switzerland |
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Cell penetrating peptides – How can they get through membranes
?
J. Seeliga, A. Zieglerb,
X. Li Blattera, P. Nervia
,A. Seeliga
a Biozentrum, University of Basel,
Basel, Switzerland
b Boston University, Proteoglycan
and Glycosaminoglycan Structure Laboratory, USA |
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Phospholipid membrane properties determining drug permeation
Marc Sutter, Tamara Fiechter, Georg Imanidis
Institute of Pharmaceutical Technology, University of Basel,
Switzerland |
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Investigating the Kinetics of Moisture-Induced
Crystallization of Amorphous Lactose
Frank Thielmanna, Daniel Burnettb
a Surface Measurement Systems,
London, United Kingdom
b Surface Measurement Systems,
Allentown, USA |
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Terahertz Spectroscopy
Terry Threlfall, Phil Taday
University of Southampton, Teraview Ltd, Cambridge, UK |
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Rational screening in solid form selection
Arjen van Langevelde, Erwin Blomsma, Stéphanie
Mulder
Avantium Technologies BV, Amsterdam, The Netherlands |
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Heat Capacities of Liquids: The Quest for a Molecular-Based
Description
Emmerich Wilhelm
Department of Physical Chemistry, University of Wien,
Austria |
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Surface Properties of Milled and Unmilled Form I Paracetamol
Powders
Daryl R. Williams, Jerry Y. Y. Heng
Dep. of Chemic.
Engineering + Chemical Technology,
Imperial College, London, UK |
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Drug Substance in Drug Product: Solid State
Identification and Particle Size Determination in Tablets
Gabriele Winter
Schering AG, Berlin, Germany |
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Chiral recognition - investigated by
IG-calorimetry and microgravimetry
Gert Wolf, J. Seidel, R. Kirchner, D. Waehlisch
Institute of Physical Chemistry, Technical University of Freiberg,
Germany |
POSTERS
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Application of
Thermal Analysis and X-Ray Diffraction Methods in the Study of
Resolutions via Derivatives
Laura Bereczkia, József Schindlerb, Petra
Bombiczc, Katalin Marthid, György Pokola,
Elemér
Fogassyb
a
Institute
of General + Analyt. Chem., Budapest Univ.
of Technol. + Econ., Hungary
b Dep. of Organic Chemical Technology, Budapest Univ.
of Technol. + Econ., Hungary
c Institute of Structural Chemistry, Hungarian Academy of Sciences, Budapest,
Hungary
d Res. Group of Techn. Analyt. Chem., Budapest Univ. of Technol. + Econ., Hungary
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Monitoring the elimination of solvents from pharmaceutical
powders by a SPME-direct method
J. Bessea, F. Bigoua,
J. -L. Luisiera, R. Nzéboa,
P. Pichlerb, R. Rosséa
a Haute Ecole Valaisanne, HEVs,
SION, Switzerland
b Brechbühler AG, SCHLIEREN,
Switzerland |
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Optimizing the stability of a commercial compound using a
high-throughput approach for forced degradation and excipient
compatibility studies
Eric Carlson, Isabel Galdo, Thomas Kudla
Symyx Technologies, Sunnyvale, CA, USA |
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Large Scale Fractionation of Polymers for
Special Applications
John Eckelt, Bernhard Anton Wolf
Institute of Physical Chemistry, University of Mainz, Germany
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Thermal and Structural Properties of Theophylline-7-acetic Acid
Ferdinando Giordanoa, Anastasia Foppolib,
Andrea Gazzanigab, Mino R. Cairac,
Sibulelo Vilakazic
a Dipartimento Farmaceutico, Università di Parma, Italia
b Istituto Chimico Farmaceutico,
Università di Milano, Italia
c Department of Chemistry,
University of Cape Town, South Africa |
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Two Polymorphs - Which One is Stable at Ambient Conditions ?
Anette Frost Jensen, Finn Junager, Susanne B. Laustsen, Pernille
Rasmussen,
Claus U. Jessen, Hanne T. Kornø, John Bondo Hansen
Novo Nordisk A/S, Research & Development,
Maaloev, Denmark
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Crystal
Polymorphs of Metazachlor: Isolation, Morphology and Crystal
Structure Analysis
Ram K. R. Jettia,
M. Haddowb,
P. Erkb,
V. Kahlenbergc,
K. Wurstd,
D. Weiganda,
J. Griessera
a
Institute of Pharmacy, University of Innsbruck, Austria
b
Research Center, BASF AG, Ludwigshafen, Germany
c
Department of Mineralogy, University of Innsbruck, Austria
d
Institute of General, Inorg.
+ Theoret.
Chem., University
of Innsbruck, Austria |
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Thermoanalytical testing of microspheres containing Diltiazem
hydrochloride and Tolperisone hydrochloride
T. Hekmatara, G.
Regdon jr., P. Sipos, I.
Erös, K. Pintye-Hódi
Department of Pharmaceutical Technology, University of Szeged,
Hungary |
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The uptake of solvents into drugs and their influence on the
stability of polymorphs
Sebastian Kaerger, Frank Stowasser, Stephanie Monnier, Michael Mutz,
Danielle Giron
Novartis Pharma AG, Chemical and Analytical Development, CH-4002
Basel |
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Release of Timolol Maleate from pH-sensitive Poly (methacrylic
acid-co-2-hydroxyethyl methacrylate) Hydrogels
I. Katimea, J.L. Escobarb, E. Hernaeza,
L. Pereza, J. Veladac
a Departamento de Quimica Fisica, Universidad del Pais
Vasco, Spain
b Instituto de Biomateriales, Universidad de la Habana,
Cuba
c GlaxoSmithKline, Weybridge, Surrey, United Kingdom |
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Adsorption and accumulation of Cd(II) ions by
Spirulina platensis cells
A. Khizanishvili, A. Belokobilsky, L. Mosulishvili, E. Ginturi, N.
Kuchava, A. Rcheulishvili
E. Andronikashvili Institute of Physics Academy of Sciences Georgia,
Tbilisi, Georgia |
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Solid-state characterization of mesalazine
bromide monohydrate
Ana Kwokala,
Michaela Horvata,
Petar Tudja aDominik Cincicb,
Ernest Meštrovica,
Biserka Cetina-Cižmeka
a
PLIVA-Research and Development, Ltd., Zagreb
b
Laboratory of General and Inorganic Chemistry, Faculty of Science,
Zagreb |
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Analytical Investigation of the Excipient
Polysorbate 80
Francine I. Lorenz, Hans R. Altorfer
Institute of Pharmaceutical Sciences, ETH Zuerich, Switzerland |
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Problems encountered in case of compounds having a low enantiotropic
transition
S.
Monnier, T. Buser, P. Piechon, M. Bellus, D. Giron
Chemical & Analytical Development, Novartis Pharma AG, Basel,
Switzerland |
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Application of Combined Thermoanalytical
Techniques on the Investigation of
Organic Compounds
Cs. Novaka, Zs. Ehena, T. F. Mourab,
L. P. Fernandesb
a Institute of General and Analytical Chemsitry,
University of Budapest, Hungary
b Departamento di Farmacia, Universidade Federal
do Rio Grande do Norto, Natal, Brazil |
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Calorimetric observation
of lactose crystallisation in skim milk and whey protein concentrate
powders
A. Raemy, F. Morgan, R. Baechler, C. Appolonia Nouzilee, G. Vuataz
Nestec Ltd., Lausanne, Switzerland |
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Equipment Qualification
for FT-IR / FT-NIR
Albrecht Rager
Bruker Optik GmbH, Ettlingen, Germany |
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Isostructural Polymorphs of the Local Anaesthetic Drugs
Falicaine and Dyclonine
Andrea C. Schmidta,
Robin K. Harrisb, Ulrich J.
Griessera,
a Department of Pharmaceutical
Technology, Univ. of Innsbruck, Innsbruck,
Austria
b Department of Chemistry,
University of Durham, United Kingdom |
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Two - Photon Excitation Fluorescence Cross -
Correlation Spectroscopy for Ligand Binding Assays
Jody L. Swifta,
David T. Cramba,
Tanya E.S. Dahmsb
a
Department of Chemistry, University of Calgary; Canada
b Department of Chemistry, University of Regina; Canada |
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Chiral and Racemic Structures of Tartrate Salts
Terry Threlfall, Thomas Gelbrich, Mike Hursthouse, Susanne Hutt, Eva
Seeger
University of Southampton, United Kingdom, University of Leipzig,
Germany |
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A Calorimetric Study of Erythritol
Luciana I. N. Tomé, A. J. Lopes Jesus, M. Margarida F. P. M. Antunes,
Teresa M. R. Maria, M. Luísa P. Leitão, M. Ermelinda S. Eusébio, J. S. Redinha
Departamento de Química, Universidade de Coimbra, Portugal |
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Applications of Raman Microscopy: Fast Scanning
Chemical Mapping of Drug Delivery Systems
S. D. Warda, S. Y. Luka,
C. E. Maddena, D. Le Rouxa,
N. Patela, A. P. Parkera,
C. J. Robertsb
a Molecular Profiles Ltd., Nottingham,
United Kingdom
bLaboratory of Biophysics + Surface Analysis, Univ. of
Nottingham, United Kingdom |
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A Silicon chip based flow-through calorimeter for
bio-chemical and screening applications
J. Lerchnera,
G. Wolfa,
M. Nietzschb, M. Krügelb
a TU
Bergakademie Freiberg, Germany
b ”Eurotronics” Ges. wiss. Gerätebau mbH, Leipzig,
Germany |
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MTDSC analysis of amorphous Nifedipine using
sinusoidal and linear modulation of temperature program
Natalija Zajca,
Geza Regdon jr.b, Klara Pintye-Hodib, Stane
Srcica
a
University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia
b University of Szeged, Department of Pharmaceutical
Technology, Szeged, Hungary |
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