Scientific Program
List of participants

Conferences - PhandTA 7

Scientific Program

AL ... Award Lecture      PL ... Plenary Lecture     KC ... Key Communication
SC ... Short Communication     PO ... Poster

By clicking on the links provided, the corresponding abstracts are available in pdf-format.

AL Award for "Applied Physical Chemistry"
Infrared-Reflection-Absorption-Spectroscopy (IRRAS) of Lipid-Peptide Interactions in Monolayers at the Air-Water Interphase

Alfred Blume

Institute of Physical Chemistry , Martin-Luther-University, Halle/Saale, D
PL Thiomers, a New Class of Polymeric Excipients
Andreas Bernkop-Schnürch
Institute for Pharmaceutical Technology, University of Wien, A
PL Crystallization, Characterization and Crystal Structure of Host-Guest Inclusion Complexes. Potential Application for Enantiomeric Resolution
A.Grandeury a, S. Tisse a, Samuel Petit a, G. Goughier b, V. Agasse a, G. Coquerel a
a Unité de Croissance Cristalline, de Chromatographie et de Modélisation Moléculaire, Sciences et Méthodes Séparatives
Laboratoire des Fonctions Azotées et Oxygénées Complexes, Université de Rouen, Mont Saint-Aignan, F
PL Magic-Angle Spinning NMR, Crystallograpy and Pharmaceutical Polymorphism
Robin K. Harris

Department of Chemistry, University of Durham, UK
PL Crystalline Polymorphism, Habits, Agglomeration States and Amorphous Phases: An Overview of the Importance of the Solid State in Pharmaceutical Development
Michel Bauer

Sanofi-Synthelabo, Toulouse, F
PL The Relationship between Passive Diffusion and Active Transport by P-Glycoprotein
Anna Seelig
, Ewa Gatlik-Landwojtowicz, Xiaochun Li Blatter
Department of Biophysical Chemistry, University of Basel, CH
PL Advances in the Science of Transdermal Drug Delivery
Georgios Imanidis

Institute of Pharmaceutical Technology, University of Basel, CH
PL Stability, Aging and Release of Drug Products: SWAXS opens new Perspectives
Peter Laggner
Austrian Academy of Sciences, and Hecus X-Ray Systems, Graz, A
PL The Solid State of Pharmaceutical Compounds. Impact of the ICHQ 6 Guideline on Industrial Development
Daniéle Giron
Novartis Pharma AG, Basel, CH
PL Probing Amorphous Relaxation and Crystallization using Master Curves and X-Ray Diffraction
David A. Engers, Lori R. Hilden, Jon L. Hilden, Kenneth R. Morris
Purdue University, West Lafayette, IN, USA
PL Hydrogen-Deuterium Exchange as a Means of Probing Water-Solid Interactions
Lynne S. Taylor
a, Matti Ahlqvist b
Purdue University, West Lafayette, IN, USA
AstraZeneca R&D Mölndal, Sweden
PL Roll Compaction / Dry Granulation of Pharmaceutical Excipients: Case Study Magnesium Stearate
Peter Kleinebudde a, Franziska Freitag b
a Institute of Pharmaceutics, University Duesseldorf, D
b Institute of Pharmaceutics and Biopharmaceutics, M.-Luther-University Halle-Wittenberg, D 
KC Impact of Dehydration Conditions on the Physical State of Anhydrous Phases Obtained by Drying of Stoichiometric Hydrates
Ulrich J. Griesser

Institute of Pharmacy, University of Innsbruck, A
KC Evolution of Polarity in Molecular Crystals
Stefan Kluge a,b, Jürg Hulliger b
Solvias AG, Basel, CH
Department of Chemistry and Biochemistry, University of Bern, CH
KC The Benefits of Microscopic Methods in the Evaluation of Binary Systems
Judith M. Rollinger
Institute of Pharmacy, University of Innsbruck, A
KC Polymorphism of Glycine: Thermodynamic and Structural Aspects
Elena V. Boldyreva a,b, Valeri A. Drebushchak a,c,d, Tatyana N. Drebushchak a,b, Igor E. Paukov d, Yulia A. Kovalevskaya d, Elena S. Shutova a,b 
Novosibirsk State University, Center of Advanced Education "Molecular Design and Ecologically Safe Technologies", Novosibirsk, RUS
b Institute of Solid State Chemistry, Siberian Branch of Russian Academy of Sciences, Novosibirsk, RUS
c Institute of Mineralogy and Petrography, Siberian Branch of Russian Academy of Sciences, Novosibirsk, RUS
d Institute of Inorganic Chemistry, Siberian Branch of Russian Academy of Sciences, Novosibirsk, RUS
KC Solid-State NMR Spectroscopy: Introduction and Application to Polymorphism Studies
Susan M. De Paul
Solvias AG, Basel, CH
KC Determination of Drug-Excipient and Drug-Solvent Interaction by Inverse Gas Chromatography
Frank Thielmann a, M. Naderi a, D. Burnett b
Surface Measurements Systems, London, UK
Surface Measurements Systems, Allentown, PA, USA
KC Solid Solutions for Drug Development Problems
Bernd Liepold
Abbott GmbH & Co KG, Ludwigshafen, D
KC Transitiometry and Spectro-Calorimetry for Research Laboratories and Industry
Jean-Pierre E. Grolier
a, Florin Dan b
a Blaise Pascal University, Aubičre, F
Gh. Asachi Technical University, Iasi, RO

Recent Development in the Kinetic and Thermodynamic Analysis of Isothermal Microcalorimetric Data: Solid State and Complex Reaction Systems
Anthony E. Beezer
Medway Sciences, University of Greenwich, Kent,UK

KC Salt and Polymorph Selection: Fundamental Topics in any Pharmaceutical Development
Magali Sautel, Patrick Dorion, Benoit Robert, My Truong
Sanofi Synthélabo Recherche, Analytical Sciences Department, Longjumeau, F
KC Fast Polymorph Screening and Data Analysis by a new High Throughput X- ray Powder Diffraction Instrument: Example of an Active Pharmaceutical Ingredient which has the Tendency to Form Solvates
S. Pfeffer
, E. Tedesco, P. Piechon, M. Bellus, D. Giron
Novartis Pharma AG, Basel, CH
KC The Solubility of Gases in Liquids
Emmerich Wilhelm
Department of Physical Chemistry, University of Vienna, A
KC Calorimetric Investigations of Sparingly Soluble Substances
Gert Wolf
Institute of Physical Chemistry, Technical University Freiberg, D
KC Characterizing the Amorphous State in a Pharmaceutical Powder Using an Automatic Moisture and Organic Vapor Sorption Analyzer
Dan Burnett, F. Thielmann, Daryl Williams
Surface Measurements Systems, London, UK
KC The "Crystalline/Amorphous State" Duality of Pharmaceutical Materials: from Concepts to Manipulation
Marc Descamps
, J.F. Willart, L.Carpentier, A De Gusseme, S. Desprez
Laboratoire de Dynamique et Structure des Matériaux Moléculaires and "Driven Pharmaceutical Materials" Group, University of Science and Technology of Lille, F
KC Supramolecular Entities in Chiral Recognition. Interpretation of Resolution Processes
Gy. Pokol
a, D. Kozma b, K. Marthi c, F. Faigl b, E. Fogassy b
Institute of General and Analytical Chemistry, Budapest University of Technology and Economics, H
b Department of Organic Chemical Technology, Budapest University of Technology and Economics, H
Hungarian Academy of Sciences – Budapest University of Technology and Economics, Research Group of Technical Analytical Chemistry, H
SC Analyzing the Crystal Purity of Mebendazole Raw Material by DRIFT Spectrometry and ANN Spectral Modelling
B.D.Glass a, S. Agatonovic-Kustrin b, M.E. Brown c, M. Mangan a, E. Mopp c, M. Aereboe d
a James Cook University, Townsville, AUS
b University of South Australia, Adelaide, AUS
c Rhodes University, Grahamstown, South Africa
d Aspen-Pharmacare Ltd, Port Elizabeth, South Africa
SC Carriers for Dry Powder Inhalers - Characterisation by Vapour Sorption and Thermal Analysis
Maike Lohrmann, Nora Anne Urbanetz, B.C. Lippold
Heinrich-Heine-University, Dusseldorf, D
SC Structural Changes of Excipients Under Stress: an Atomic Force Microscopy Investigation
Laura Bond a, C.J. Roberts a, S. Allen a, A.Shivji b
Laboratory of Biophysics and Surface Analysis, School of Pharmacy, University of Nottingham, UK
b Pfizer Global Research and Development, Kent, UK
SC Effect of Drying and Cross-Linking on the Thermo-Analytical Characteristics of Gelatine
Martin Renner, Bernhard C. Lippold
Institute for Pharmaceutical Technology, Heinrich-Heine-University Duesseldorf, D
SC Temperature and Structural Changes of Excipients during Tableting
A.G. Schmidt, K.M. Picker
Martin-Luther-University, Halle/Wittenberg, D
SC TAM III - A New Generation (micro/nano-) Calorimetric System from Thermometric for Isothermal, Step-wise and Slow Temperature Scanning Applications
Peter Johansson

Thermometric AB, Järfälla, S
SC High Throughput Screening for Pre-formulation Polymorphs and Salt Forms
Eric Carlson
Symyx Technologies, Inc., USA
SC How to Bring Thermal Analysis Software in Line with 21 CFR, Part 11
G. Kaiser
, I. Issaev, E. Kaisersberger
Netzsch Gerätebau, Selb, D
SC Rate and Mechanism of Lactose Hydration
Theodore Sokoloski a, Johannes Opfermann b, Jeffrey Brum a
Lee Katrincic a, Fred Vogt a
GlaxoSmithKline, Collegeville and King of Prussia, PA, USA
Netzsch, Gerätebau GmbH, Selb, D
SC The Structural and Thermodynamic Basis of Oswald's Rule
Terry Threlfall
Southampton University, UK
SC Solvent Exchange Mechanisms among Pharmaceutical Crystals: From Topotactic to Destructive-Reconstructive Processes
F. Mallet, Samuel Petit, G. Coquerel
University of Rouen, F
SC The Thermally Stimulated Current (TSC), a Spectroscopy Technique for Exploration of the Materials Structure
Christine Mayoux
Setaram, Caluire, F
SC Raman Spectroscopy: An Emerging Analyzer Tool for the Pharmaceutical Industry
Ian R. Lewis, Harry Owen, Bruno P. Lenain
Kaiser Optical SARL, Lyon, F
PO Whisker Growth of Glibenclamide in Solid Dispersions
S.E. Bartsch, U.J. Griesser
Department of Pharmaceutical Technology, University of Innsbruck, A
PO Investigation of Antioxidant Properties of Pharmaceuticals by Voltammetry
N.V. Bashkatova, E.I. Korotkova, Yu.A. Karbainov, E.A. Mamaeva, 
A.A Bakibaev

Tomsk Politechnic University, RUS
PO Thermospectroscopic Studies in the Stretching Region of Betaxolol and Betaxolol Hydrochloride
J. Canotilho, M.S.C. Cruz, M.L.P. Leităo, A.T. de Sousa, J.S. Redinha
Faculty of Pharmacy, University of Coimbra, P
PO Studies on the Stability of Atenolol During the Heating Programme of Thermoanalytical Methods
R.A.E. de Castro, M.A.R. Gonsalves, F.S. Cosata, M.L.P. Leităo, A.M.d‘A.R. Gonsalves, J.S. Redinha
Faculty of Pharmacy, University of Coimbra, P
PO Solid State Characterization of Glyburide-Cyclodextrin Coground Products
M. Cirri, F. Maestrelli, F. Righi, P. Mura
Department of Pharmaceutical Sciences, University of Florence, Florence, Italy
PO Characterization of the Solid Phase of Pipemidic Acid at Equilibrium with Saturated Solutions in Solvent Mixtures
S. Romero a, P. Bustamante a, B. Escalera a, M. Cirri b, P. Mura b
a Facultad de Farmacia, Univ. de Alcalŕ de Henares, Madrid, E
b Facoltŕ di Farmacia, Univ. di Firenze, I
PO Thermodynamic Studies of the Polymorphs of Sulfathiazole
Valeri A. Drebushchaka,b,c, M.A. Mikhailenkoa,c, E.V. Boldyrevaa,c, T.N. Drebushchaka,c, T.P. Shakhtshneidera,c, Vladimir V. Boldyreva,c 
a  Research + Education Center & Molecular Design + Ecologica ll Safe Technologies, Novosibirsk State University, RUS
b  Institute of Mineralogy, Novosibirsk, RUS
c  Institute of Solid State Chemistry, Novosibirsk, RUS
PO A Comparison of DSC, TMDSC and DMA Techniques for Studying the Influence of Production Methods on Spray Dried Particles
John C. Duncan a, Paul Royall b, Kurt Pommerenke c
Triton Technology Ltd., Mansfield, UK
b Department of Pharmacy, Kings College, London UK
c Trilogica GmbH, Dortmund, D
PO Investigation of the Drug Substance Torasemide Using Coupled Thermoanalytical Methods (TG-FTIR, TG-MS)
Zsuzsanna Éhen
a , Judith M. Rollingerb, Csaba Nováka , Katalin Marthi
Budapest University of Technology and Economics and Research Group for a Technical Analytical Chemistry of Hungarian Academy of Sciences, H
b Institute of Pharmacy, University of Innsbruck, A
PO Probe into the Physical Properties of a Gelucire® 44/14 Pharmaceutical Formulation
H. Elmaleh, C.Neves, M.-A.Perrin
Aventis Pharma,  Vitry sur Seine, F
PO Thermal-Dependent Dehydration of NSB L-Tartrate Monohydrate: Solid-state characterisation of Anhydrous Form II and Form III
B. Frřstrup, K.S. Jensen
NeuroSearch A/S, DK
PO Study of Crystallization of Drug Substances under Solvent Vapour Atmosphere by Microcalorimetry
Stéphanie Garnier, Michael Mutz, Daničle Giron
Novartis Pharma AG, Basel, CH
PO Effect of Magnetic Field Gradient on Biomass Growth and Cd(II) Binding Process by S.platensis Cells
E.N. Ginturi, F.Kh. Akopov, A.N. Rcheulishvili, E.S. Gelagutashvili, 
E.Y. Efremova, A.I. Belokobilsky
Georgian Academy of Sciences, Tbilisi, Georgia
PO Use of Thermoanalytical Combined Techniques for Process Development
Daničle Giron, Miriam Bellus, Stéphanie Garnier, Christianne Goldbronn, Philippe Piéchon, Sabine Pfeffer
Chemical and Analytical Development, Novartis Pharma AG, Basel, CH
PO Chemical Shifts and Crystal Structure of Methylnitroacetanilide
Robin K. Harris, Phuong Y. Ghi
Department of Chemistry, University of Durham, Durham, UK
PO Wettability Behaviour of Form I Paracetamol Crystals
D. Williams, J. Heng
Imperial College London, UK
PO The Synthesis and Physicochemical Investigations of Peroxide Layered Structures as Possible Long-Lived Drug Substances
E.Ippolitov, T.Tripolskaya, I.Pokhabova, G.Pilipenko, P.Prikhodchenko
Russian Academy of Sciences, Moscow, RUS
PO Zn(II) Binding by Spirulina platensis Cells at Different Nutrient Loads and Exposure Times (Atomic Absorption Analysis)
A.I. Khizanishvili
Georgian Academy of Sciences, Tbilisi, Georgia
PO Fully-Automated Ultrasensitive Differential Scanning Calorimeter for High-Throughput Studies of Biopharmaceutical Formulations and Drug Discovery
L.-N. Lin, J.F. Brandts, J.M. Brandts, V. Plotnikov, V. Frasca
MicroCal, LLC, Central Milton Keynes, UK
PO Development of Nitric Oxide Releasing Silicone Polymers
A. Osvald, Ö. Wagner, G. Liptay
Technical University Budapest, H
PO Thermal Analysis of Crown Ether Complexes
L. Bereczki, K. Marthi, P. Huszthy, Gy. Pokol
Instituteof Generaland Analytical Chemistry, Technical University of Budapest, H
PO Influence of Magnetic Field (80-100 ers.) and Laser Irradiation (λ=899 nm) on Blue-Green Microalgae Spirulina platensis Heat Production
A. Belokobilski, L. Mchedlishvili, F. Akopov, M. Kiladze, Sh. Barbakadze, M. Gorgoshidze, J. Monaselidze
Georgian Academy of Sciences , Tbilisi, Georgia
PO Microcalorimetric Investigation of Collagen Stability at Norm and Pathology of Cartilaginous Tissue
I. Mesropyana, Sh. Barbakadzea, M. Gorgoshidzea, R. Kvavadzea, Th. Burjanadzeb, J. Monaselidzea
E. Andronikashvili Institute of Physics, Georgian Academy of Sciences, Tbilisi, Georgia
b A. Natishvili Institute of Experimental Morphology, Georgian Academy of Sciences, Tbilisi, Georgia
PO Characterisation of the Metastable Form in Coffein Samples
P.R. Müller, U.J. Griesser
Department of Pharmaceutical Technology, University of Innsbruck, A
PO Crystal Polymorphism of Prilocaine Hydrochloride
V. Niederwanger, A.C. Schmidt, U.J. Griesser
Department of Pharmaceutical Technology, University of Innsbruck, A
PO The Stability of the Free Eudragit NE Films Stored under Different Conditions
J. Bajdik a, G. Regdon jr. a, P. Fazekas b, P. Szabó-Révész a, I. Eros a
K. Pintye-Hódi
a Department of Pharmaceutical Technology, University of Szeged,  Szeged, H
b Egis Pharmaceuticals, Lacta Factory, Körmend, H
PO Detection of Cyclization with DSC Method
G. Regdon jr.a, L. Károlyházy b, O. Éliás b, P. Mátyus b, I. Erosa, K. Pintye-Hódi
a University of Szeged, Pharmaceutical Technology Department, Szeged, H
b Semmelweis University, Department of Organic Chemistry, Budapest, H
PO Optimization of Nitrazepam Solubility and Thermoanalytical Investigation of their some Complexes
H. Kelemena, B. Tokésa, G. Regdon jr.b
a Faculty of Pharmacy, University of Medicine and Pharmacy, Târgu Mures, RO
b University of Szeged, Pharmaceutical Technology Department, Szeged, H
PO How Many Polymorphs Has Frusemide ?
Sohrab Karahmi, Mike Hursthouse, Ron Roberts, Terry Threlfall
Southampton University, UK
PO DSC Measurements of Full Thickness Mice Skin, a Way to Evaluate the Mechanism of Permeation Enhancement of Highly Lipophilic Drugs
R. Schiller a, H.-W. Motzkus a, A. Funke b, C. Günther c, R. Lipp b
a Pharmaceutical-Development, Thermal Analysis, Schering-AG Berlin, D
b Pharmaceutical-Development, Oral Dosage Forms, Schering-AG Berlin, D
c Preclinical Development, Schering-AG, D
PO Crystal Polymorphism of Local Anaesthetic Drugs: A Summary
A.C. Schmidt, U.J. Griesser
Department of Pharmaceutical Technology, University of Innsbruck, A
PO Gravitational Action Through Medium In BP Measurement Procedure
Akinori Shiraishi
Shiraishi Hospital, Okayama-City, Japan
PO Study of Polymorphism of Carvedilol
M. Smrkolj, A. Vajs, R. Zupet, M. Grcman
KRKA, D.D., Research and Development, Novo mesto, Slovenia
PO Monte-Carlo Simulation as a Promising Tool for Polymorph Screening"
Volker Thome, Heike Pontius, Manuela Dörich, Michael Herrmann
Fraunhofer ICT, Pfinztal, D
PO Vapour Pressure Determination of Pharmaceutical Powders
D. Williamsa, D. Wilsona, R. Storeyb, P. Basfordb
Imperial College London, UK
b Pfizer Research, Sandwich, UK
PO Nifedipine Solid Dispersions with PEG 4000 and Gelucire 53/10 - a DSC Study
Natalija Zajc, Stane Srcic
University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia
PO Comparison of Index pI50 of New Cholinesterase Inhibitors with Rivastigmine and Galanthamine
Pavla Zdražilová a, Šárka Štepánková b, Karel Komers a, Karel Ventura b
Alexander Cegan c
a Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Rep.
b Department of Analytical Chemistry
c Department of Biological and Biochemical Sciences

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