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Workshop 2
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Conferences - PhandTA 10

List of Contributions



Inverse Gas Chromatography – Basics and advanced Applications in Dependence of Relative Humidity
Jürgen Adolphs, Porotec GmbH, Hofheim, Germany


Prediction of miscibility and solid solubility of amorphous drugs with polymers
Hisham Al-Obaidi, Stephen Brocchini, Graham Buckton
Department of Pharmaceutics, School of Pharmacy, University of London, UK


Crystallization of Phosphoantigens: Application to IPH1101, from first Nuclei to industrial  Applications
 Eric Aubin1, Servane Coste2 and Gérard Coquerel2,
1 Innate Pharma, Marseille, France
2 Unité de Croissance Crystalline et de Modélisation Moléculaire, UPRES E.A. 3233, IRCOF,Mont Saint Aignan, France


Control of the relative Vapor Pressure of organic Liquids in microcalorimetric
Perfusion Experiments

Julia Baronsky, Institut für Pharmazeutische Technologie und Biopharmazie,
Heinrich-Heine-Universität, Düsseldorf, Germany
Bayer HealthCare AG, Leverkusen, Germany

The Development and Application of a Photocalorimeter designed for stability  
Studies of Pharmaceuticals
Anthony E. Beezer, School of Pharmacy, University of London, London, UK


Carbamacepine: Anhydrate or Dihydrate
Fritz Blatter, Esther Büchel, and Rolf Hilfiker, Solvias AG
Klybeckstrasse 191, CH-4002  Basel


Black, white and gray or - Polymorphs-Amorphs-Solvates-Cocrystals-Salts -, which 
are the differences, amongst and between

Roland Boese, Chemistry Department, University Duisburg-Essen, Essen, Germany

Metastable Forms of Pharmaceuticals
Elena V. Boldyreva, Institute of Solid State Chemistry, Siberian Branch of the
Russian Academy of Science, Novosibirsk, Russia

Reducing inter-particle Interactions by using lower scale Spacer Particles –
computational Modeling of Host Particle Coverage

Carsten Bresges, Institut für Pharmazeutische Technologie und Biopharmazie
Heinrich-Heine-Universität, Düsseldorf, Germany

The Discontinuous Isoberibolic Thermal Analysis, a new Tool for Description of
Phase Diagrams with molecular Components

Y. Cartigny, University of Rouen, France

DSC and mechanical Activation Studies for pharmaceutical applications
Galina G. Chernik, Div. Physical Chemistry, St. Petersburg State University
Petrodvorets, St. Retersburg, Russia

Use of combined Thermal Analysis and Calorimetric Methods for the Characterization of  organic Salts as Drug Substances
Danielle Giron, P. Piechon, S. Monier, M. Mutz, M. Descourvieres, R. Frömrich,
T. Buser and F. Stowasser
Novartis Pharma AG, Chemical and Analytical Development, CH-4002, Basel

Thermoanalytical Methods – applications in Medicine
Beverly Glass1 and M.E. Brown2
1 School of Pharmacy and Molecular Sciences, James Cook University
Townsville, Australia
 2 Chemistry Department, Rhodes University, Grahamstown, South Africa

Impact of heterochiral Interactions during the Growth of enantio-pure Materials.
How can we evaluate them?

Arnaud Grandeury, H. Lorenz, and A. Seidel-Morgenstern, Cephalon Inc., France

Crystal Forms of amiloride hydrochloride
Ulrich Griesser, M.Tischler and B. Binna
Institute for Pharmacy, University of Innsbruck, Innsbruck, Austria

Polymer Microstructures: Elaboration, Modification and Characterization by Supercritical Fluids
Yves-Marie Corre, Mohamed Baba, Jean-Marie Nedelec, Jean-Pierre Grolier
Université Blaise Pascal, 24 Ave. des Landais, 63177 Aubière, France

Atomic Force Microscopy – an Approach to understand Polymer Adhesion on the
cores during the Dry Coating Process

Caroline Kablitz, Institut für Pharmazeutische Technologie und Biopharmazie
Heinrich-Heine-Universität, Düsseldorf, Germany

Dehydration of Carbamazepine Dihydrate
Kyriakos Kachrimanis, Department of Pharmaceutical Technology
Aristotle University of Thessaloniki, Greece

Physicochemical Properties as crucial Factors for the API and the related Drug Products
Heidi Lopez de Diego, Preformulation, Lundbeck, Denmark, DK

Physicochemical Properties as crucial Factors for the API and the related Drug Products
Heidi Lopez de Diego, Preformulation, Lundbeck, Denmark, DK   

Leveraging quantitative Solubility Measurements into Polymorph Screening Diversity
Michael Millan, Avantium Technologies BV, Amsterdam, The Netherlands

Basic Chemical Entities and their related Derivatives (Hydrates, Solvates, Salts, and
others Compounds): Definition of Polymorphism, Amorphicity, Pseudopolymorphism

Erwin Marti, Basel, CH

Flowability and Fluidization measurements of nanoparticle covered Powders for use
in Dry Powder Inhalers

Victoriya Mykhaylova, Institut für Pharmazeutische Technologie und Biopharmazie Heinrich-Heine-Universität, Düsseldorf, Germany

Can we elucidate chiral Discrimination from physical and structural
Characterizations?  A case Study with Host-Guest Complexes

Samuel Petit, University of Rouen, France

Polymorphism of Squaramides: Study of a Model System with a Hydrogen Bonding Donor-Acceptor Ability
Anna Portell, Rafael Barbas, Cristina Puigjager, Rafel Prohens
Serveis Cientificotècnics, Universitat de Barcelona, Barcelona, Spain

Characterization of Biodegradable Poly(lactic Acid) by Thermal Analysis
Marek Pyda, ATHAS Lab, USA


Transitiometry of Substances with a pharmaceutical Importance
Stanislaw Randzio, Polish Academy of Sciences, Warsaw, Poland

Promiscuity and Specificity in ABC Transporters
Anna Seelig, Biozentrum, University of Basel, Basel


Detergents, Peptides, and Microdomains in Membranes
Joachim Seelig, Biozentrum, University of Basel, Basel

High Speed imaging Developments in Raman Spectroscopy
Riccardo Tagliapietra, Renishaw Group
New Mills, Wotton-under-Edge, Gloucestershire, UK

Raman Spectroscopy: An emerging analyzer tool for the Pharmaceutical Industry
Carsten Uerpmann. Kaiser Optical Systems SARL
5 allée du Moulin Berger, 69130 Ecully,France

Dry Powder Inhalers – Influencing inter-particle Forces and fine Particle Fractions
of ordered Mixtures by chemically modifying the carrier Surface

Nora Urbanetz, Institut für Pharmazeutische Technologie und Biopharmazie
Heinrich-Heine-Universität, Düsseldorf, Germany


An Overview of Applications of Isothermal Microcalorimetry in Pharmaceutical

Peter Vikegard, Thermometric AB, Järfälla, Sweden

Characterization of Moisture in Pharmaceutical Solids
Matthias Wagner, Rudolf Riesen, Mettler-Toledo AG, Schwerzenbach, CH

Quantification of low Levels of amorphous Materials using deuterium exchange and FT- Raman Spectroscopy
P.T. Whiteside, M.W. George, S.Y. Luk, C.E. Madden, A.P. Parker, P. Turner and N. Patel Molecular Profiles Ltd., Nottingham Business Park, NG8 6PX Nottingham


Hydrophobic Effects in Biophysical Chemistry
Emmerich Wilhelm, Institute of Physical Chemistry, University of Vienna
Vienna, Austria

Evaluation of Molecular Motions of Liquid Crystals Amphiphilic Di-block Copolymer under Carbon Dioxide Pressure
Takeshi Yamada1, Tomokazu Iyoda11, Hiroshisa Yoshida11, Jean-Pierre E. Grolier2
 1Tokyo Metropolitan University, Tokyo, Japan
 2Université Blaise Pascal, Aubière, France


Thermodynamic and structural analysis of self-assemble alkyl quaternary ammonium Salts and related Polymers
 Hirohisa Yoshida, Tokyo Metropolitan University, Tokyo, Japan

Poster Presentations

Variations of the Coating Formulation for Dry Powder Coating
F. Klar, and Nora A. Urbanetz, Institute for Pharmaceutics and Biopharmaceutics
Heinrich-Heine-University, 40225 Duesseldorf, Germany

Rigid amorphous Phase of Biodegradable Poly(lactic Acis)
A. Magon1 and Marek Pyda2
1Department of Chemistry, The University of Technology, Rzeszow, Poland
2ATHAS-MP Company, Knoxville, Tennessee, USA

Automated Multi-Sample Moisture Sorption Analysis
Erwin Marti1, Ulrich Griesser2, Michchael Noisternig2 and Jürgen Dillenz3
1APCh Marti Consulting, CH-4054 Basel
2Institute of Pharmacy, University of Innsbruck, 6020 Innsbruck, Austria
3Projekt Messtechnik, 89007 Ulm, Germany

Determination of Powder Flow Properties of Calcium Phosphate Samples with
Mercury Intrusion Porosimetry (MIP)

M.F. Noisternig, W. Wertl, U.J. Griesser, Institute for Pharmacy
University of Innsbruck, Innsbruck, Austria


High-Throughput study on the Impact of Freeze-Drying Conditions on the Stability of Co-
Lyophilized Protein-Saccharide Formulations

FrankThielmann1, Daniel Burnett2, Kevin Ward3, and Isobel Cook3
1 Surface Measurement Systems Ltd., Alperton, Middlesex, UK
2 Surface Measurement Systems Ltd., Allentown, PA 18103, USA
3 Biopharma Technology Ltd., Winchester SO23 OLD, UK

Crystallization of metastable Polymorphs of Phenobarbitone by isomorphic Seeding
N. Zencirci, V. Kahlenberg, U.J. Griesser, Institute for Pharmacy
University of Innsbruck, Innsbruck, Austria

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